They brought slaves and slaveholding traditions with them, and quickly started cultivating crops similar to those in Middle Tennessee and Kentucky: hemp and tobacco. Ralls County was one of several along the Mississippi River settled in the early years primarily by European-American migrants from the Upper South, especially Kentucky and Tennessee. Ralls County is part of the Hannibal, MO Micropolitan Statistical Area, which is also included in the Quincy-Hannibal, IL-MO Combined Statistical Area. The county was organized Novemand named for Daniel Ralls, Missouri state legislator. As of the 2020 census, the population was 10,355.
Ralls County is a county located in the northeastern portion of the U.S.
